A water-insoluble polymer matrix that physically captures surface-bound cells and cell-free DNA — then releases its full cargo during mechanical disruption. No irreversible substrate retention. No lost evidence.
Learn moreConventional swabs impose a structural ceiling on DNA recovery: up to 76% of collected material remains irreversibly bound within the fiber matrix during extraction. The Omni-Matrix eliminates this ceiling. Sprayed onto smooth non-porous evidence surfaces, the polymer film incorporates all surface-bound cellular material. During mechanical disruption, the matrix releases its entire captured DNA cargo directly to extraction — with no irreversible substrate binding.
Single-use 1 mL spray bottles apply a thin, even film from approximately 6 inches. The formulation is non-toxic and compatible with standard magnetic bead extraction systems including the Omni-Mag™ system.
Unlike swabs, which require a spin-basket transfer step that permanently loses a fraction of captured DNA, the matrix releases its full captured cargo upon mechanical disruption — reducing both DNA loss and cross-contamination risk.
Spray → allow 20 minutes to dry → scrape dried film with sterile plastic blade → transfer to extraction tube. Fully compatible with standard forensic laboratory workflows and capillary electrophoresis platforms.
Once applied at the scene, the dried matrix film physically encapsulates surface-bound DNA, potentially protecting against degradation, UV exposure, and transit-related cellular loss during packaging.
The NFSTC (2016) and Ramirez / John Jay College of Criminal Justice (2019) studies provide complementary validation from controlled glass substrates to real touch DNA on five forensically relevant mock evidence types.
Blood stains on glass at extreme 1:200 dilution. PurFlock® Ultra swab achieved only 27–39% at equivalent dilutions — directly relevant to trace casework concentrations.
Three-contributor mixed fingerprint on glass. A 24.8 percentage-point advantage over contemporary swab technology, directly reducing minor-contributor dropout risk.
243.63 pg median vs. 16.64 pg for FLOQSwab from touch DNA on five non-porous mock evidence types. Statistically significant: Mann-Whitney U, p = 0.024.
Matrix samples yielded full or high partial GlobalFiler™ profiles in 52% of cases versus 24% for FLOQSwab — more than doubling CODIS-eligible upload rate.
Across five donors and five mock evidence types, Omni-Matrix reduced the negative (no donor alleles) profile rate from 44% to 17.4% — a 2.5× reduction in collection failure.
Compared with 2.6% median per-sample allele recovery for swab collection — a more-than-27-fold improvement in the proportion of expected alleles successfully recovered.
Validated for smooth non-porous surfaces across a range of forensic, biometric, and genomic applications where trace-level DNA collection is critical.
Weapons, door handles, steering wheels, packaging, cable ties, masks, and digital devices. Superior allele recovery from touch deposits in the critical window between evidence collection and cold case degradation.
Rapid biometric-grade DNA collection from identity documents, border hardware, and entry surfaces. Compatible with high-throughput microfluidic platforms for rapid field identification and database matching.
15-fold median yield improvement enables SNP array and whole-genome sequencing from trace-level deposits previously below reliable amplification thresholds — expanding the genotyping landscape for low-template samples.
Maximising DNA yield from degraded, contaminated, or low-transfer surfaces in mass casualty events. The closed-film collection mechanism reduces cross-contamination risk in multi-victim environments.
Apply Omni-Matrix K105 solution from approximately 6 inches onto the non-porous evidence surface. A uniform thin film forms as the polymer solution contacts the substrate, incorporating surface-bound cells and cell-free DNA.
Allow approximately 20 minutes for the water-insoluble matrix to dry and fully encapsulate all surface DNA. The bright visible film aids documentation and confirms complete coverage of the sampling zone.
Scrape the dried film mechanically with a sterile plastic blade into a collection tube. The complete matrix is captured — no spin-basket, no transfer loss, no residual substrate-bound DNA.
The matrix releases its entire DNA cargo upon mechanical disruption, delivering it directly into lysis buffer. Compatible with Omni-Mag™ magnetic bead purification and standard downstream STR, SNP, and WGS workflows.
"The mechanistic explanation — complete physical release of captured DNA from the insoluble matrix during disruption, eliminating the substrate-bound DNA retention that limits all swab technologies — is well-supported by both studies."
Journal of Forensic Sciences, Trace DNA Collection Review — Omni-Matrix SectionTwo independent institutions — the National Forensic Science Technology Center (NFSTC, 2016) and John Jay College of Criminal Justice (Ramirez, 2019) — using different substrates, deposit types, and experimental designs reached the same conclusion: the Omni-Matrix system substantially outperforms contemporary swab technology for trace DNA collection from smooth non-porous surfaces.
Key assumptions: $1.50 ASP · $0.45 COGS at scale · 50,000 units/lab/yr · Beachhead: 150 labs by Yr 3 · 24–30 month runway on Series A
Average selling price at target volume. Low-cost consumable with high replacement rate per active lab.
High-margin consumable model. Recurring revenue with low regulatory burden versus device classification.
Projected from 150-lab beachhead in Yr 3 expanding through Federal, Military, and International phases.
Break-even at Year 3. 4–8× revenue multiple implies $160M–$560M exit valuation at target strategic acquirer.
Capital deployed across manufacturing scale-up, commercial launch, and validation milestones required for Federal and SWGDAM adoption.
Cap table post-Series A: Founders 60% · Series A 25% · Options 15%
| Feature | Cotton Swab | Flocked Swab | Omni-Matrix™ |
|---|---|---|---|
| DNA Recovery | 20–50% | 40–60% | ~100% |
| Release Efficiency | Poor | Moderate | >95% |
| Trace DNA Performance | Poor | Moderate | Excellent |
| Matrix Releases Completely | No | No | Yes |
| Direct-to-Lysis | No | No | Yes |
| NGS Compatible | Limited | Yes | Optimized |
Direct sales to 400+ US crime labs. AAFS conferences. Beta with 3+ labs. SWGDAM validation.
FBI QAS approval. DOD forensic units. Federal law enforcement contracts.
CE marking. UK, EU, Australia. Distributor partnerships.
Rapid DNA platforms. SNP genomics, immigration screening, pharmacogenomics.
Strategic Exit Targets
Partnership· Licensing · Acquisation
First-mover IP position with an issued US utility patent, additional device utility filings planned, and manufacturing process protected as trade secret.
Confidential — for accredited investor use only · US Patent 10,228,307 · BioFunctions, Inc.
© 2025 GeneLink Inc. Omni-Matrix™ is a trademark of GeneLink Inc.
For forensic laboratory and research use.